Flexact BP is the first member of the Flexact series of Sartorius Stedim Biotech. The system is designed for preparation of buffers that are essential for stabilizing target molecules and providing for their optimal production conditions. In biopharmaceutical processes, buffers, such as sodium phosphate, Tween and Tris, are particularly used in cultivation and fermentation as well as purification to maintain pH, salt content and other parameters of biologics within a desired range. The Flexact BP system is based on a multifunctional central operating module (COM), which accommodates pre-configured single-use assemblies and, moreover, a pump and a control unit. Flexact BP addresses the entire development cycle and production capacity needs from 50 to 1000 l for buffer preparation. The integration of monitoring and control features for pH, temperature, pump speed and fluid level control reflects a new milestone for implementing process-relevant analytical tools. The integrated controls enable users to perform other tasks during the buffer preparation process without the need to supervise the system. In combination with a Flexel Levmixer system and multiple Palletanks, the multifunctional COM lets users install, operate and monitor a unit operation completely based on single-use components.

The entire configurable Flexact BP solution consists of a Flexel Levmixer system, a weighing platform, a multiple bag assembly with Palletanks and the central operating module. Its compact design enables users to easily maneuver it even in tight production spaces.